Article
HTRF analysis of soluble huntingtin in PHAROS PBMCs.
Neurology - 24 Sept 2013
Moscovitch-Lopatin Miriam, Goodman Rachel E, Eberly Shirley, Ritch James J, Rosas H Diana, Matson Samantha, Matson Wayne, Oakes David, Young Anne B, Shoulson Ira, Hersch Steven M
Abstract excerpt
OBJECTIVE: We measured the levels of mutant huntingtin (mtHtt) and total huntingtin (tHtt) in blood leukocytes from Prospective Huntington At-Risk Observational Study (PHAROS) subjects at 50% risk of carrying the Huntington disease mutation using a homogeneous time-resolved fluorescence (HTRF) as...
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