Article
A polymorphism in ORMDL3 is associated not only with asthma without rhinitis but also with chronic obstructive pulmonary disease.
Journal of investigational allergology & clinical immunology - 1 Jan 2013
Balantic M, Rijavec M, Flezar M, Camlek T, Hudoklin I, Kosnik M, Korosec P, Suskovic S
Abstract excerpt
BACKGROUND: Asthma is a heterogeneous disease, and asthmatic patients without rhinitis more commonly have fixed airway obstruction, a feature that is also typical of chronic obstructive pulmonary disease (COPD). The Dutch hypothesis suggests that both COPD and asthma have common genetic risk factors. The purpose of this study was to assess the association between the polymorphism rs4795405 in the known asthma...
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