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Article

ARMS2 interference leads to decrease of proinflammatory mediators.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 1 Nov 2013

Zeng Fanxing, Zhang Min, Xu Yiting, Xu Haifeng

Abstract excerpt

BACKGROUND: Age-related macular degeneration (AMD) is a major cause of irreversible blindness among elderly people in developed countries. Many studies suggested that age-related maculopathy susceptibility 2 (ARMS2) is the second major susceptibility gene for AMD. Increasing evidence was found recently that inflammatory processes and oxidative stress may contribute to the pathogenesis of AMD. Meanwhile, the...

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Identifiers

PMID: 23959158
DOI: 10.1007/s00417-013-2442-0

Genes

ARMS2
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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