Article
Elevated C-reactive protein levels and ARMS2/HTRA1 gene variants in subjects without age-related macular degeneration.
Molecular vision - 31 Dec 2010
Yasuma Tetsuhiro R, Nakamura Makoto, Nishiguchi Koji M, Kikuchi Masato, Kaneko Hiroki, Niwa Toshimitsu, Hamajima Nobuyuki, Terasaki Hiroko
Abstract excerpt
PURPOSE: To investigate the association between the serum high sensitivity C-reactive protein (hs-CRP) levels and variants in age-related maculopathy susceptibility 2 (ARMS2)/HtrA serine peptidase 1 (HTRA1) genes in normal subjects with no evidence of age-related macular degeneration (AMD). METHODS: After clinical evaluation, information related to medical and social history was collected from 476 Japanese...
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