Article
Telomere dynamics in mice and humans.
Seminars in hematology - 1 Apr 2013
Calado Rodrigo T, Dumitriu Bogdan
Abstract excerpt
Telomeres are ribonucleoprotein structures capping the end of every linear chromosome. In all vertebrates, they are composed of TTAGGG repeats coated with specific protecting proteins. Telomeres shorten with each mitotic cell division, but telomerase, a reverse transcriptase, elongate telomeres in very specific cells, such as embryonic and adult stem cells. Although telomere sequence is identical in mice and...
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