Article
Impaired memory and reduced sensitivity to the circadian period lengthening effects of methamphetamine in mice selected for high methamphetamine consumption.
Behavioural brain research - 1 Nov 2013
Olsen Reid H J, Allen Charles N, Derkach Victor A, Phillips Tamara J, Belknap John K, Raber Jacob
Abstract excerpt
Drug abuse runs in families suggesting the involvement of genetic risk factors. Differences in addiction-related neurobiological systems, including learning and memory and circadian rhythms, may exist prior to developing addiction. We characterized the cognitive phenotypes and the free-running circadian period of mouse lines selectively bred for high methamphetamine (MA) drinking (MA high drinking or MAHDR) and...
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