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Distinct Gene Expression Signatures in Lynch Syndrome and Familial Colorectal Cancer Type X

12 Aug 2013

Abstract excerpt

INTRODUCTION: Heredity is estimated to cause at least 20% of colorectal cancer. The hereditary nonpolyposis colorectal cancer subset is divided into Lynch syndrome and familial colorectal cancer type X (FCCTX) based on presence of mismatch repair (MMR) gene defects. PURPOSE: We addressed the gene expression signatures in colorectal cancer linked to Lynch syndrome and FCCTX with the aim to identify candidate genes...

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Share to Colorectal Cancer Screening and Detection
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PMID: 23951239
DOI: 10.1371/journal.pone.0071755

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