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Article

Familial Colorectal Cancer Type X (FCCTX) and the correlation with various genes-A systematic review.

Current problems in cancer - 1 Jan 2000

Nejadtaghi Mahdieh, Jafari Hamideh, Farrokhi Effat, Samani Keihan Ghatreh

Abstract excerpt

Familial Colorectal Cancer Type X (FCCTX) is a type of hereditary nonpolyposis colorectal cancer in accordance to Amsterdam criteria-1 for Lynch syndrome, with no related mutation in mismatch repair gene. FCCTX is microsatellite stable and is accounted for 40% of families with Amsterdam criteria-1 with a high age of onset. Thus, the carcinogenesis of FCCTX is different compared to Lynch syndrome. In addition to...

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Share to BRCA2 Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

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Source

Identifiers

PMID: 29096939
DOI: 10.1016/j.currproblcancer.2017.10.002

Genes

BRCA2
APC
BRAF
GALNT12
KRAS
NTS
RASSF9
RPS20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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