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Article

Genotypic and phenotypic susceptibility of emerging avian influenza A viruses to neuraminidase and cap-dependent endonuclease inhibitors.

Antiviral research - 1 Sept 2024

Andreev Konstantin, Jones Jeremy C, Seiler Patrick, Kandeil Ahmed, Webby Richard J, Govorkova Elena A

Abstract excerpt

Avian influenza outbreaks, including ones caused by highly pathogenic A(H5N1) clade 2.3.4.4b viruses, have devastated animal populations and remain a threat to humans. Risk elements assessed for emerging influenza viruses include their susceptibility to approved antivirals. Here, we screened >20,000 neuraminidase (NA) or polymerase acidic (PA) protein sequences of potentially pandemic A(H5Nx), A(H7Nx), and...

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Identifiers

PMID: 38986873
DOI: 10.1016/j.antiviral.2024.105959
PMCID: PMC11466321

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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