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Article

Antagonistic and stimulative roles of ADAR1 in RNA silencing.

RNA biology - 1 Aug 2013

Nishikura Kazuko, Sakurai Masayuki, Ariyoshi Kantaro, Ota Hiromitsu

Abstract excerpt

Adenosine deaminases acting on RNA (ADARs) are involved in RNA editing that converts adenosine residues to inosine specifically in double-stranded RNAs (dsRNA). This A-to-I RNA editing pathway and the RNA interference (RNAi) pathway seem to interact antagonistically by competing for their common dsRNA substrates. For instance, A-to-I editing of certain microRNA (miRNA) precursors by ADAR1 and ADAR2 inhibits their...

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Source

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Identifiers

PMID: 23949595
DOI: 10.4161/rna.25947
PMCID: PMC3817143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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