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Article

Progressive Age-Related Cognitive Decline in Tau Mice

10 Oct 2013

Abstract excerpt

Age-related cognitive decline and neurodegenerative diseases are a growing challenge for society. Accumulation of tau pathology has been proposed to partially contribute to these impairments. This study provides a behavioral characterization during aging of transgenic mice bearing tau mutations. THY-Tau22 mice were evaluated at ages wherein tau neuropathology in this transgenic mouse model is low (3-4 months),...

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PMID: 23948912
DOI: 10.3233/jad-130110

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