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Study of insulin resistance in cybrid cells harboring diabetes-susceptible and diabetes-protective mitochondrial haplogroups.

Mitochondrion - 1 Nov 2013

Weng Shao-Wen, Kuo Hsiao-Mei, Chuang Jiin-Haur, Lin Tsu-Kung, Huang Hui-Lin, Lin Hung-Yu, Liou Chia-Wei, Wang Pei-Wen

Abstract excerpt

AIM: This study aims to elucidate the independent role of mitochondria in the pathogenesis of insulin resistance (IR). METHODS: Cybrids derived from 143B osteosarcoma cell line and harboring the same nuclear DNA but different mitochondrial haplogroups were studied. Cybrid B4 (the major diabetes-s...

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Identifiers

PMID: 23948373
DOI: 10.1016/j.mito.2013.08.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23948373-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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