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Article

Estimating successive cancer risks in Lynch Syndrome families using a progressive three-state model.

Statistics in medicine - 20 Feb 2014

Choi Yun-Hee, Briollais Laurent, Green Jane, Parfrey Patrick, Kopciuk Karen

Abstract excerpt

Lynch Syndrome (LS) families harbor mutated mismatch repair genes,which predispose them to specific types of cancer. Because individuals within LS families can experience multiple cancers over their lifetime, we developed a progressive three-state model to estimate the disease risk from a healthy...

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Identifiers

PMID: 23946183
DOI: 10.1002/sim.5938

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23946183-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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