Article
Modified capture-recapture estimates of the number of families with Lynch syndrome in Central Ohio.
Familial cancer - 1 Jan 2019
Ranola John Michael O, Pearlman Rachel, Hampel Heather, Shirts Brian H
Abstract excerpt
Past methods for estimating the population frequency of familial cancer syndromes have used cases and controls ignoring the familial nature of genetic disease. In this study we modified the capture-recapture method from ecology to estimate the number of families in central Ohio with Lynch syndrome (LS). We screened 1566 colorectal cancer cases and 545 endometrial cancer cases in central Ohio from 1999 to 2005 and...
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