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Article

Health benefits and cost-effectiveness of primary genetic screening for Lynch syndrome in the general population.

Cancer prevention research (Philadelphia, Pa.) - 1 Jan 2011

Dinh Tuan A, Rosner Benjamin I, Atwood James C, Boland C Richard, Syngal Sapna, Vasen Hans F A, Gruber Stephen B, Burt Randall W

Abstract excerpt

In current clinical practice, genetic testing to detect Lynch syndrome mutations ideally begins with diagnostic testing of an individual affected with cancer before offering predictive testing to at-risk relatives. An alternative strategy that warrants exploration involves screening unaffected individuals via demographic and family histories, and offering genetic testing to those individuals whose risks for...

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Identifiers

PMID: 21088223
DOI: 10.1158/1940-6207.CAPR-10-0262
PMCID: PMC3793254

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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