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Article

Identification of lethal microRNAs specific for head and neck cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2013

Lindenbergh-van der Plas Marlon, Martens-de Kemp Sanne R, de Maaker Michiel, van Wieringen Wessel N, Ylstra Bauke, Agami Reuven, Cerisoli Francesco, Leemans C René, Braakhuis Boudewijn J M, Brakenhoff Ruud H

Abstract excerpt

PURPOSE: The prognosis of head and neck squamous cell carcinomas (HNSCC) remains disappointing and the development of novel anti-cancer agents is urgently awaited. We identified by a functional genetic screen microRNAs that are selectively lethal for head and neck cancer cells but not for normal cells. We further investigated the genes targeted by these microRNAs. EXPERIMENTAL DESIGN: A retroviral expression...

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Identifiers

PMID: 23942092
DOI: 10.1158/1078-0432.CCR-12-2295

Genes

ATM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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