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Article

The potent tumor suppressor miR-497 inhibits cancer phenotypes in nasopharyngeal carcinoma by targeting ANLN and HSPA4L.

Oncotarget - 3 Nov 2015

Wang Shumin, Mo Yingxi, Midorikawa Kaoru, Zhang Zhe, Huang Guangwu, Ma Ning, Zhao Weilin, Hiraku Yusuke, Oikawa Shinji, Murata Mariko

Abstract excerpt

Nasopharyngeal carcinoma (NPC) is a malignancy with poor prognosis that is endemic to Southeast Asia. We profiled microRNAs (miRNAs) of NPCs using microarrays and confirmed the results by quantitative RT-PCR. The results revealed that seven miRNAs were significantly up-regulated, and six miRNAs were down-regulated, in NPC tissues relative to noncancerous nasopharyngeal epithelia (NNE). Expression of miR-497 was...

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Identifiers

PMID: 26486082
DOI: 10.18632/oncotarget.5651
PMCID: PMC4742149

Genes

ANLN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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