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Article

A Letter Matters: ADRB2 rs1042713 c.46A Modulates Anti-osteogenic Effect of Epinephrine in Human Mesenchymal Stem Cells.

Stem cell reviews and reports - 1 Oct 2026

Krasnova Olga, Sopova Julia, Borodii Valeriia, Semenova Polina, Bystrova Olga, Neganova Irina

Abstract excerpt

Osteoporosis (OP) is a systemic bone disease affecting millions worldwide, characterized by long-term asymptomatic development that manifests in low-energy fractures. Due to their high stability, genetic markers represent a promising strategy for early diagnostics. The ADRB2 rs1042713 polymorphism is one such marker, considered as a potential predictor for OP. Although the anti-osteogenic role of the...

Read the complete abstract on PubMed

Topics

Humans
Mesenchymal Stem Cells
Epinephrine
Receptors, Adrenergic, beta-2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Cell Differentiation

Osteogenesis

Polymorphism, Single Nucleotide

Alleles

Source

Identifiers

PMID: 42384302
DOI: 10.1007/s12015-026-11185-7

Genes

ADRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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