Article
Genetic mapping of specific interactions between Aedes aegypti mosquitoes and dengue viruses.
PLoS genetics - 1 Jan 2013
Fansiri Thanyalak, Fontaine Albin, Diancourt Laure, Caro Valérie, Thaisomboonsuk Butsaya, Richardson Jason H, Jarman Richard G, Ponlawat Alongkot, Lambrechts Louis
Abstract excerpt
Specific interactions between host genotypes and pathogen genotypes (G×G interactions) are commonly observed in invertebrate systems. Such specificity challenges our current understanding of invertebrate defenses against pathogens because it contrasts the limited discriminatory power of known invertebrate immune responses. Lack of a mechanistic explanation, however, has questioned the nature of host factors...
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