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Quantitative genetics of Aedes aegypti vector competence for dengue viruses: towards a new paradigm?

Trends in parasitology - 1 Mar 2011

Lambrechts Louis

Abstract excerpt

Similar to many other host-pathogen interactions, the vector competence of Aedes aegypti for dengue viruses appears to be determined by genotype-by-genotype interactions, whereby the outcome of infection depends on the specific combination of mosquito and virus genotypes. This can complicate efforts to dissect the genetic basis of vector competence in nature because it obscures mapping between genotype and...

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PMID: 21215699
DOI: 10.1016/j.pt.2010.12.001

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