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Using genetic variation in Aedes aegypti to identify candidate anti-dengue virus genes

4 Jul 2019

Abstract excerpt

BACKGROUND: Transcriptomic profiling has generated extensive lists of genes that respond to viral infection in mosquitoes. These gene lists contain two types of genes; (1) those that are responsible for the insect's natural antiviral defense mechanisms, including some known innate immunity genes, and (2) genes whose change in expression may occur simply as a result of infection. As genetic modification tools for...

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PMID: 31272403
DOI: 10.1186/s12879-019-4212-z

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