Article
Genetic specificity and potential for local adaptation between dengue viruses and mosquito vectors.
BMC evolutionary biology - 9 Jul 2009
Lambrechts Louis, Chevillon Christine, Albright Rebecca G, Thaisomboonsuk Butsaya, Richardson Jason H, Jarman Richard G, Scott Thomas W
Abstract excerpt
BACKGROUND: Several observations support the hypothesis that vector-driven selection plays an important role in shaping dengue virus (DENV) genetic diversity. Clustering of DENV genetic diversity at a particular location may reflect underlying genetic structure of vector populations, which combined with specific vector genotype x virus genotype (G x G) interactions may promote adaptation of viral lineages to...
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