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Dengue and chikungunya virus loads in the mosquito Aedes aegypti are determined by distinct genetic architectures

12 Apr 2023

Abstract excerpt

Aedes aegypti is the primary vector of the arboviruses dengue (DENV) and chikungunya (CHIKV). These viruses exhibit key differences in their vector interactions, the latter moving more quicky through the mosquito and triggering fewer standard antiviral pathways. As the global footprint of CHIKV continues to expand, we seek to better understand the mosquito's natural response to CHIKV-both to compare it to...

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PMID: 37043515
DOI: 10.1371/journal.ppat.1011307

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