Article
A shrinkage method for testing the Hardy-Weinberg equilibrium in case-control studies.
Genetic epidemiology - 1 Nov 2013
Zang Yong, Yuan Ying
Abstract excerpt
Testing for the Hardy-Weinberg equilibrium (HWE) is often used as an initial step for checking the quality of genotyping. When testing the HWE for case-control data, the impact of a potential genetic association between the marker and the disease must be controlled for otherwise the results may b...
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