Article
Heterogeneity of tumor endothelial cells.
Cancer science - 1 Nov 2013
Hida Kyoko, Ohga Noritaka, Akiyama Kosuke, Maishi Nako, Hida Yasuhiro
Abstract excerpt
Tumor blood vessels play important roles in tumor progression and metastasis. Thus, targeting tumor blood vessels is an important strategy for cancer therapy. Tumor endothelial cells (TECs) are the main targets of anti-angiogenic therapy. Although tumor blood vessels generally sprout from pre-existing vessels and have been thought to be genetically normal, they display a markedly abnormal phenotype, including...
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