Article
Heterogeneity of the tumor vasculature.
Seminars in thrombosis and hemostasis - 1 Apr 2010
Nagy Janice A, Chang Sung-Hee, Shih Shou-Ching, Dvorak Ann M, Dvorak Harold F
Abstract excerpt
The blood vessels supplying tumors are strikingly heterogeneous and differ from their normal counterparts with respect to organization, structure, and function. Six distinctly different tumor vessel types have been identified, and much has been learned about the steps and mechanisms by which they form. Four of the six vessel types (mother vessels, capillaries, glomeruloid microvascular proliferations, and...
Topics
- Angiogenesis Inhibitors
- Animals
- Humans
- Neoplasms
- Neovascularization, Pathologic
- Phenotype
- Vascular Endothelial Growth Factor A