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Computational validation of ABCB1 gene polymorphism and its effect on tacrolimus dose concentration/levels in renal transplant individuals of South India.

Computers in biology and medicine - 1 Dec 2021

Mallina Haritha, Elumalai Ramprasad, F D Paul Solomon, George Priya Doss C, Udhaya Kumar S, Ramanathan Gnanasambandan

Abstract excerpt

Patients with end-stage renal failure require hemodialysis and peritoneal dialysis; however, kidney transplantation is considered a better treatment option for renal failure patients, improving their quality of life and longevity. Among several potent immunosuppressive agents, tacrolimus (TAC) has shown progressive improvement in the graft survival rates after renal transplantation. Fifty kidney transplant...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34735949
DOI: 10.1016/j.compbiomed.2021.104971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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