Article
Repeated triggering of sporulation in Bacillus subtilis selects against a protein that affects the timing of cell division.
The ISME journal - 1 Jan 2014
Siebring Jeroen, Elema Matthijs J H, Drubi Vega Fátima, Kovács Akos T, Haccou Patsy, Kuipers Oscar P
Abstract excerpt
Bacillus subtilis sporulation is a last-resort phenotypical adaptation in response to starvation. The regulatory network underlying this developmental pathway has been studied extensively. However, how sporulation initiation is concerted in relation to the environmental nutrient availability is poorly understood. In a fed-batch fermentation set-up, in which sporulation of ultraviolet (UV)-mutagenized B. subtilis...
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