Article
Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component.
The Journal of biological chemistry - 9 Dec 2016
Myers Cullen L, Li Franco K K, Koo Byoung-Mo, El-Halfawy Omar M, French Shawn, Gross Carol A, Strynadka Natalie C J, Brown Eric D
Abstract excerpt
The cell wall of most Gram-positive bacteria contains equal amounts of peptidoglycan and the phosphate-rich glycopolymer wall teichoic acid (WTA). During phosphate-limited growth of the Gram-positive model organism Bacillus subtilis 168, WTA is lost from the cell wall in a response mediated by the PhoPR two-component system, which regulates genes involved in phosphate conservation and acquisition. It has been...
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