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Article

Single cell analysis of gene expression patterns of competence development and initiation of sporulation in Bacillus subtilis grown on chemically defined media.

Journal of applied microbiology - 1 Sept 2006

Veening J-W, Smits W K, Hamoen L W, Kuipers O P

Abstract excerpt

AIM: Understanding the basis for the heterogeneous (or bistable) expression patterns of competence development and sporulation in Bacillus subtilis. METHODS AND RESULTS: Using flow cytometric analyses of various promoter-GFP fusions, we have determined the single-cell gene expression patterns of competence development and initiation of sporulation in a chemically defined medium (CDM) and in biofilms. CONCLUSIONS:...

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PMID: 16907804
DOI: 10.1111/j.1365-2672.2006.02911.x

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