Article
Differential gene expression in genetically identical sister cells: the initiation of sporulation in Bacillus subtilis.
Molecular microbiology - 1 May 2005
Yudkin Michael D, Clarkson Joanna
Abstract excerpt
Early in sporulation, the cell divides asymmetrically to give two sister compartments, a smaller prespore and a larger mother cell. Differential gene expression in these compartments depends on the regulation of the first sporulation-specific sigma factor, sigma(F), which is activated only in the prespore. Regulation relies on the interactions of four proteins -sigma(F), its antisigma SpoIIAB (which also has...
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