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Article

Analysis of CFH, TLR4, and APOE polymorphism in India suggests the Tyr402His variant of CFH to be a global marker for age-related macular degeneration.

Investigative ophthalmology & visual science - 1 Sept 2006

Kaur Inderjeet, Hussain Avid, Hussain Nazimul, Das Taraprasad, Pathangay Avinash, Mathai Annie, Hussain Anjli, Nutheti Rishita, Nirmalan Praveen K, Chakrabarti Subhabrata

Abstract excerpt

PURPOSE: To screen polymorphisms in complement factor-H (CFH), toll-like receptor 4 (TLR4), and APOE genes as potential risk factors for age-related macular degeneration (AMD) in Indian patients. METHODS: One hundred patients with AMD and 120 normal control subjects were screened for the polymorphisms by restriction digestion and resequencing. Five intragenic SNPs in CFH were screened to generate haplotype data...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16936080
DOI: 10.1167/iovs.05-1430

Genes

CFH
APOE
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of CFH, TLR4, and APOE polymorphism in India suggests the Tyr402His variant of CFH to be a global marker for age-related macular degeneration.PMID 16936080Read ↗

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