Article
The role of molecular genetic factors in age-related macular degeneration.
Arquivos brasileiros de oftalmologia - 1 Jan 2000
Almeida Luciana Negrão Frota de, Carolino Rachel Melilo, Sperandio Diogo Cazelli, Nehemy Márcio Bittar, De Marco L A
Abstract excerpt
Age-related macular degeneration (AMD) is the most frequent cause of irreversible blindness in the elderly in developed countries. Although the etiology of AMD remains largely unknown, numerous studies have suggested that both genes and environmental risk factors significantly influence the risk of developing AMD. Recently, single nucleotide polymorphisms, DNA sequence variations found within the complement...
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