Article
The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins.
Mutation research - 1 Sept 1990
Giometti C S, Tollaksen S L, Gemmell M A, Taylor J, Hawes N, Roderick T
Abstract excerpt
We have used two-dimensional gel electrophoresis (2DE) coupled with computer-assisted data analysis to analyze liver-protein expression in mice known to be heterozygous carriers of recessive lethal mutations induced in In(1)1Rk or In(7)13Rk inversion stocks by exposure to either triethylene melamine or ionizing radiation. Carriers of 8 different mutations and corresponding littermate controls (average of 17...
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