The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins.

doi:10.1016/0165-1218(90)90098-m

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Article

The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins.

Mutation research - 1 Sept 1990

Giometti C S, Tollaksen S L, Gemmell M A, Taylor J, Hawes N, Roderick T

Abstract excerpt

We have used two-dimensional gel electrophoresis (2DE) coupled with computer-assisted data analysis to analyze liver-protein expression in mice known to be heterozygous carriers of recessive lethal mutations induced in In(1)1Rk or In(7)13Rk inversion stocks by exposure to either triethylene melam...

Topics

Animals
Chromosome Inversion
Electrophoresis, Gel, Two-Dimensional
Female
Genes, Recessive
Genetic Markers
Heterozygote
Isoenzymes
Liver
Male
Mice
Mice, Inbred C57BL
Mutation
Proteins

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