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Article

Identification of proteins that modify cataract of mouse eye lens.

Proteomics - 1 Dec 2008

Hoehenwarter Wolfgang, Tang Yajun, Ackermann Renate, Pleissner Klaus-Peter, Schmid Monika, Stein Robert, Zimny-Arndt Ursula, Kumar Nalin M, Jungblut Peter R

Abstract excerpt

The occurrence of a nuclear cataract in the eye lens due to disruption of the alpha3Cx46 connexin gene, Gja3, is dependent on strain background in a mouse model, implicating factors that modify the pathology. The differences upon cataractogenesis in the urea soluble proteins of the lens of two mouse strains, C57BL/6J and 129/SvJ, were analyzed by a comparative proteomics approach. Determination of the complete...

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Source

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Identifiers

PMID: 19003866
DOI: 10.1002/pmic.200800380
PMCID: PMC3018240

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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