Comparisons of genetic variability detected among mouse blood proteins using one- and two-dimensional electrophoreses.

doi:10.1007/BF00554380

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Article

Comparisons of genetic variability detected among mouse blood proteins using one- and two-dimensional electrophoreses.

Biochemical genetics - 1 Oct 1990

Sands T W, Hill K A, Petras M L

Abstract excerpt

Comparisons of the sensitivities of one-dimensional (1D) and two-dimensional (2D) electrophoreses to detect genetic variability have generally shown that the 2D approach appears to be two- to five-fold less sensitive than conventional 1D approaches. Concerns about the validity of this conclusion...

Topics

Animals
Animals, Wild
Blood Proteins
Electrophoresis, Gel, Two-Dimensional
Electrophoresis, Polyacrylamide Gel
Female
Genetic Variation
Male
Mice
Mice, Inbred Strains
Species Specificity

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