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Article

Angiogenin induces modifications in the astrocyte secretome: relevance to amyotrophic lateral sclerosis.

Journal of proteomics - 8 Oct 2013

Skorupa Alexandra, Urbach Serge, Vigy Oana, King Matthew A, Chaumont-Dubel Séverine, Prehn Jochen H M, Marin Philippe

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting lower and upper motoneurons. Recent studies have shown that both motor neurons and non-neuronal neighbouring cells such as astrocytes and microglia contribute to disease pathology. Loss-of-function mutations in the angiogenin (ANG) gene have been identified in ALS patients. Angiogenin is enriched in motor neurons and exerts...

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Identifiers

PMID: 23920243
DOI: 10.1016/j.jprot.2013.07.028

Genes

ANG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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