Article
Angiogenin induces modifications in the astrocyte secretome: relevance to amyotrophic lateral sclerosis.
Journal of proteomics - 8 Oct 2013
Skorupa Alexandra, Urbach Serge, Vigy Oana, King Matthew A, Chaumont-Dubel Séverine, Prehn Jochen H M, Marin Philippe
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting lower and upper motoneurons. Recent studies have shown that both motor neurons and non-neuronal neighbouring cells such as astrocytes and microglia contribute to disease pathology. Loss-of-function mutations in the...
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