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Article

Proteomic analysis of cerebrospinal fluid in amyotrophic lateral sclerosis

31 Mar 2016

Abstract excerpt

The present study used comparative proteomic analysis of cerebrospinal fluid (CSF) in amyotrophic lateral sclerosis (ALS) patients in order to identify proteins that may act as diagnostic biomarkers and indicators of the pathogenesis of ALS. This analysis was performed using isobaric tags for relative and absolute quantitation (iTRAQ) technology, coupled with 2-dimensional liquid chromatography/mass spectrometry....

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PMID: 27284291
DOI: 10.3892/etm.2016.3210

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