Article
Impact of apolipoprotein E on Alzheimer's disease.
Current Alzheimer research - 1 Oct 2013
Hauser Paul S, Ryan Robert O
Abstract excerpt
A key feature of Alzheimer's disease (AD) is deposition of extracellular amyloid plaque comprised chiefly of the amyloid β (Aβ) peptide. Studies of Aβ have shown that it may be catabolized by proteolysis or cleared from brain via members of the low-density lipoprotein receptor family. Alternative...
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