NAD(P)H: quinone oxidoreductase 1 and NRH:quinone oxidoreductase 2 polymorphisms in papillary thyroid microcarcinoma: correlation with phenotype.

doi:10.3349/ymj.2013.54.5.1158

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Article

NAD(P)H: quinone oxidoreductase 1 and NRH:quinone oxidoreductase 2 polymorphisms in papillary thyroid microcarcinoma: correlation with phenotype.

Yonsei medical journal - 1 Sept 2013

Lee Junguee, Kim Koon Soon, Lee Min Ho, Kim Yeon Soo, Lee Min Hee, Lee Seong Eun, Kim Yong Kyung, Ryu Min Jeong, Kim Soung Jung, Choi Min Jeong, Jo Young Suk

Abstract excerpt

PURPOSE: NAD(P)H:Quinone Oxidoreductase 1 (NQO1) C609T missense variant (NQO1*2) and 29 basepair (bp)-insertion/deletion (I29/D) polymorphism of the NRH:Quinone Oxidoreductase 2 (NQO2) gene promoter have been proposed as predictive and prognostic factors for cancer development and progression. The purpose of this study is to investigate the relationship between NQO1/NQO2 genotype and clinico-pathological features...

Topics

Adult
Carcinoma, Papillary
DNA Mutational Analysis
Female
Genetic Predisposition to Disease
Humans
Immunohistochemistry
Male
Middle Aged
Multivariate Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagenesis, Insertional

Mutation, Missense

NAD(P)H Dehydrogenase (Quinone)

Phenotype

Polymorphism, Genetic

Prognosis

Promoter Regions, Genetic

Retrospective Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 23918565
DOI: 10.3349/ymj.2013.54.5.1158
PMCID: PMC3743184

Genes

NQO1
NQO2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-23918565-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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