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Article

Risk factors associated with aggressive tumor phenotypes in papillary thyroid microcarcinoma: a systematic review and meta-analysis.

Frontiers in endocrinology - 1 Jan 2026

Orgoványi Máté, Rancz Anett, Dolhascu Anca, Agócs Gergely, Szentes Boglárka Lilla, Sipter Emese, Hegyi Péter, Kovács Gábor László

Abstract excerpt

Introduction: In line with current guidelines, risk stratification in papillary thyroid microcarcinoma (PTMC) has shifted from simple diameter-based assessments to evaluation of individual tumor biology. Therefore, this study aimed to investigate how baseline clinical and molecular risk factors influence aggressive PTMC phenotypes. Methods: Registered in PROSPERO (CRD42024603662), we searched PubMed, Embase, and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42466333
DOI: 10.3389/fendo.2026.1876912
PMCID: PMC13372712

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