Article
Methylation changes in mature sperm deoxyribonucleic acid from oligozoospermic men: assessment of genetic variants and assisted reproductive technology outcome.
Fertility and sterility - 1 Nov 2013
Montjean Debbie, Ravel Célia, Benkhalifa Moncef, Cohen-Bacrie Paul, Berthaut Isabelle, Bashamboo Anu, McElreavey Kenneth
Abstract excerpt
OBJECTIVE: To characterize a potential genetic cause for methylation errors described in oligozoospermia. DESIGN: Analysis of PEG1/MEST-DMR and H19-DMR methylation level in sperm, in parallel with the study of several genes on the Y chromosome, DNMT3A, and DNMT3L. Clinical outcome was also looked...
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