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Impact of DNA methylation of the human mesoderm-specific transcript (MEST) on male infertility

1 Oct 2023

Abstract excerpt

Male infertility accounts for nearly 40%–50% of all infertile cases. One of the most prevalent disorders detected in infertile men is errors in the MEST differentially methylated region (DMR), which has been correlated with poor sperm indexes. The aim of our study was to characterize the methylation pattern of the MEST gene, along with assessing seminal factors and chromatin condensation in sperm samples from...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 37928396
DOI: 10.1016/j.heliyon.2023.e21099

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