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Article

NDRG2 positively regulates E-cadherin expression and prolongs overall survival in colon cancer patients

29 Jul 2013

Abstract excerpt

To discover the molecular mechanism of N-Myc downstream-regulated gene 2 (NDRG2), a newly found differentiation-related tumor suppressor, the relationships between NDRG2 and E-cadherin were investigated in tumor cells and tissues. Positive correlations between the expression of E-cadherin and NDRG2 were shown in several colon cancer cell lines as well as in colon cancer tissues. According to the transcription...

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PMID: 23900729
DOI: 10.3892/or.2013.2642

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