Article
Possible association between common variants of the phenylalanine hydroxylase (PAH) gene and memory performance in healthy adults.
Behavioral and brain functions : BBF - 30 Jul 2013
Teraishi Toshiya, Sasayama Daimei, Hori Hiroaki, Yamamoto Noriko, Fujii Takashi, Matsuo Junko, Nagashima Anna, Kinoshita Yukiko, Hattori Kotaro, Ota Miho, Fujii Sayaka, Kunugi Hiroshi
Abstract excerpt
BACKGROUND: Phenylalanine hydroxylase (PAH) is the enzyme that metabolizes phenylalanine, an essential amino acid required for catecholamine synthesis. Rare mutations in PAH are causal to phenylketonuria (PKU), an autosomal recessive disease characterized by neuropsychiatric symptoms including intellectual disability. We examined whether there is an association between common single nucleotide polymorphisms...
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