Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploring Subpopulations for Epidemiological Precision Nutrition Research: The Example of Phenylalanine Hydroxylase (PAH) Genetic Variation.

Nutrients - 4 Jun 2026

Dhawan Anoushka, Khan Sophia M, Fennell Madison L, Cho Clara E, Monk Jennifer M, Keathley Justine R

Abstract excerpt

Background/Objectives: Biological factors such as genetics contribute to nutrition-related outcomes, but nutritional epidemiological studies often lack consideration of genetics despite evidence of their functional impacts on health and cognition. Phenylalanine hydroxylase (PAH) genetic variation has been hypothesized to influence health and cognitive outcomes due to evidence of metabolic perturbations in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Executive Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to PAH gene

Share to Genetic Variation

Share to Heterozygote

Share to Phenylalanine Hydroxylase

Share to Phenylketonurias

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 42280454
DOI: 10.3390/nu18111811
PMCID: PMC13259265

Genes

PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploring Subpopulations for Epidemiological Precision Nutrition Research: The Example of Phenylalanine Hydroxylase (PAH) Genetic Variation.PMID 42280454Read ↗

Are Carriers Unaffected? A Literature Review of Metabolic and Health Outcomes among Genetic Carriers of Phenylketonuria.Semantic proximity Read ↗

Similarities and differences in key diagnosis, treatment, and management approaches for PAH deficiency in the United States and EuropeSemantic proximity Read ↗

Development of the Executive Function, Attention, and Speed Symptom Inventory (EASSI) for PhenylketonuriaSemantic proximity Read ↗

Cognitive profile and mental health in adult phenylketonuria: A PKU-COBESO study.Semantic proximity Read ↗

5-year retrospective analysis of patients with phenylketonuria (PKU) and hyperphenylalaninemia treated at two specialized clinics.Semantic proximity Read ↗

Phenylketonuria, co‐morbidity, and ageing: A reviewSemantic proximity Read ↗

Mapping the functional landscape of frequent phenylalanine hydroxylase (PAH) genotypes promotes personalised medicine in phenylketonuria.Semantic proximity Read ↗

The PICO Study: Impact of Phenylalanine on Cognitive, Cerebral and Neurometabolic Parameters in Adult Patients with Phenylketonuria: a Randomized, Placebo-Controlled, Crossover, Non-inferiority TrialSemantic proximity Read ↗

Causal relationships between genetically determined metabolites and human intelligence: A Mendelian randomization studySemantic proximity Read ↗

General intelligence and executive functioning are overlapping but separable at genetic and molecular pathway levels: An analytical review of existing GWAS findings.Semantic proximity Read ↗

Association Between the Genetic Risk for Attention-Deficit/Hyperactivity Disorder and Cognitive Function in Older Age: The MYHAT Population-Based Study.Semantic proximity Read ↗

The implications of genomics on the nursing care of adults with neuropsychiatric conditions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.