Article
Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML.
The New England journal of medicine - 9 May 2013
Maxson Julia E, Gotlib Jason, Pollyea Daniel A, Fleischman Angela G, Agarwal Anupriya, Eide Christopher A, Bottomly Daniel, Wilmot Beth, McWeeney Shannon K, Tognon Cristina E, Pond J Blake, Collins Robert H, Goueli Basem, Oh Stephen T, Deininger Michael W, Chang Bill H, Loriaux Marc M, Druker Brian J, Tyner Jeffrey W
Abstract excerpt
BACKGROUND: The molecular causes of many hematologic cancers remain unclear. Among these cancers are chronic neutrophilic leukemia (CNL) and atypical (BCR-ABL1-negative) chronic myeloid leukemia (CML), both of which are diagnosed on the basis of neoplastic expansion of granulocytic cells and exclusion of genetic drivers that are known to occur in other myeloproliferative neoplasms and...
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