Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Point mutations in the ICR2 motif of brome mosaic virus RNAs debilitate (+)-strand replication.

Virology - 1 Sept 1990

Pogue G P, Marsh L E, Hall T C

Abstract excerpt

Sequences at the 5' termini of the genomic RNAs of brome mosaic virus (BMV) and other (+)-stranded RNA viruses have been shown (L.E. Marsh and T.C. Hall, 1987, Cold Spring Harbor Symp. Quant. Biol. 52, 331-341) to resemble the ICRs 1 and 2 (A and B boxes) of tRNA genes, with the complementary sequences at the 3' termini of the (-) strands resembling the ICR2 motif of methionine initiator tRNA genes (L.E. Marsh,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Kinetics
Share to Molecular Sequence Data

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Promoter Regions, Genetic

Share to Regulatory Sequences, Nucleic Acid

Share to RNA, Viral

Share to Virus Replication

Source

Identifiers

PMID: 2389549
DOI: 10.1016/0042-6822(90)90388-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Point mutations in the ICR2 motif of brome mosaic virus RNAs debilitate (+)-strand replication.PMID 2389549Read ↗

Unique nucleotide differences in the conserved 3' termini of brome mosaic virus RNAs are maintained through their optimization of genome replication.Semantic proximity Read ↗

Repair of the tRNA-like CCA sequence in a multipartite positive-strand RNA virus.Semantic proximity Read ↗

A minimal RNA promoter for minus-strand RNA synthesis by the brome mosaic virus polymerase complex.Semantic proximity Read ↗

Template sequence near the initiation nucleotide can modulate brome mosaic virus RNA accumulation in plant protoplasts.Semantic proximity Read ↗

Sensitivity of brome mosaic virus RNA1 replication to mutations in the 3' tRNA-like structure implies a requirement for sustained synthesis of replicase protein 1a.Semantic proximity Read ↗

Replicase-binding sites on plus- and minus-strand brome mosaic virus RNAs and their roles in RNA replication in plant cells.Semantic proximity Read ↗

Recombination and polymerase error facilitate restoration of infectivity in brome mosaic virus.Semantic proximity Read ↗

Interference in trans with brome mosaic virus replication by RNA-2 bearing aminoacylation-deficient mutants.Semantic proximity Read ↗

Mutant viral RNAs synthesized in vitro show altered aminoacylation and replicase template activities.Semantic proximity Read ↗

Effects of alterations of primer-binding site sequences on human immunodeficiency virus type 1 replicationSemantic proximity Read ↗

Requirements for brome mosaic virus subgenomic RNA synthesis in vivo and replicase-core promoter interactions in vitro.Semantic proximity Read ↗

The Mauriceville retroplasmid reverse transcriptase initiates cDNA synthesis de novo at the 3' end of tRNAs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.