Article
Mutant viral RNAs synthesized in vitro show altered aminoacylation and replicase template activities.
Nature - 1 Jan 2000
Dreher T W, Bujarski J J, Hall T C
Abstract excerpt
A remarkable feature of the genomic RNAs of several plant viruses is the presence at the 3' end of a region that exhibits tRNA-like functions, including aminoacylation. The three genomic and single subgenomic RNAs of brome mosaic virus (BMV) accept tyrosine in vitro and in vivo, the smallest 3' fragment that can be aminoacylated being about 135 nucleotides long. The roles of the tRNA-like properties are...
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