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Article

Mutant viral RNAs synthesized in vitro show altered aminoacylation and replicase template activities.

Nature - 1 Jan 2000

Dreher T W, Bujarski J J, Hall T C

Abstract excerpt

A remarkable feature of the genomic RNAs of several plant viruses is the presence at the 3' end of a region that exhibits tRNA-like functions, including aminoacylation. The three genomic and single subgenomic RNAs of brome mosaic virus (BMV) accept tyrosine in vitro and in vivo, the smallest 3' f...

Topics

Mosaic Viruses
Mutation
Plasmids
RNA, Viral
Templates, Genetic
Tyrosine-tRNA Ligase
Virus Replication

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 6472477
DOI: 10.1038/311171a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-6472477-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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