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Article

Recombination and polymerase error facilitate restoration of infectivity in brome mosaic virus.

Journal of virology - 1 Feb 1993

Rao A L, Hall T C

Abstract excerpt

The tRNA-like structure present in the 3' noncoding region of each of the four virion RNAs of brome mosaic virus possesses a conserved A-67-U-A-65 (67AUA65) sequence. Four mutations in this region (67UAA65, 67GAA65, and 67CAA65, each with a double base change, and 67GUA65, containing a single point mutation), previously shown in vitro to be defective in minus-strand promoter function, were introduced into...

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Identifiers

PMID: 8419651
DOI: 10.1128/JVI.67.2.969-979.1993
PMCID: PMC237451

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